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Cognitive tests

  • Learning and memory        

  • Problem solving

 

Psycho-emotional
behavioral tests

  • Anxiety-like behavior

  • Fear-like behavior

  • Depression-like behavior

  • Stereotyped behaviors

  • Explorative behavior

  • Sociability

  • Behavioral flexibility

  • Stress

 
Environment effects

  • Perinatal environment 

  • Enriched environment

  • Constraint-induced movement therapy (CIMT)

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Analysis of developmental milestones

  • Body weight, pinnae detachment, eye opening, incisor eruption

  • Righting reflex, visual placing 

  • Negative geotaxis, tactile startle

  • Nest seeking response

  • Auditory startle

  • Bar holding and vertical screen.

  • Clasping behavior

 

Daily activities

  • Barrowing 

  • Home cage activity

  • Nesting

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Addiction

  • Alcohol addiction

  • Chocolate or palatable food addiction

  • Compulsive eating

 

Functional tests

  • Locomotor activity

  • Spontaneous locomotor activity

  • Feeding behavior

  • Sexual behavior

  • Heart rate and blood pressure

  • Oxygen saturation, breath rate, pulse and breath distention

IN VIVO  STUDIES

​​Neurological functions

  • Reflexes

  • Motor coordination

  • Sedation

  • Ischemia

  • Epilepsy 

  • Huntington disease 

  • EEG

  • In vivo brain transplants

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Surgical techniques

  • Traumatic brain injury (tbi)

  • Glaucoma acute and chronic

  • Neuropathic pain (sciatic nerve injury)

  • Spinal cord lesions

  • Central nervous system and in uterus grafting

  • Microsurgery

  • In utero electroporation

  • Demyelination focal injury (lysolecithin)

  • Toxic transient demyelination (cuprizone)

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Brain tumor models

  • In vivo models of glioblastoma (grafts of mouse or human glioblastoma cell lines)

  • In vivo pharmacological treatments

  • MRI-based longitudinal analyses

  • Histological investigations

  • End-point analyses

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Administration routes

  • Enteral routes: oral (gavage, capsule, diet), rectal 

  • Parenteral routes: intracerebral, intravenous, intramuscular, subcutaneous, intraperitoneal

  • Local routes: skin, ocular, intranasal, intravaginal, buccal

  • Adeno and retroviral injections

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Animal species

  • Mouse (Mus musculus)

  • Rat (Rattus Norvegicus)

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