Cognitive tests
  • Learning and memory        

  • Problem solving

 

Psycho-emotional
behavioral tests
  • Anxiety-like behavior

  • Fear-like behavior

  • Depression-like behavior

  • Stereotyped behaviors

  • Explorative behavior

  • Sociability

  • Behavioral flexibility

  • Stress

 
Environment effects
  • Perinatal environment 

  • Enriched environment

  • Constraint-induced movement therapy (CIMT)

Analysis of developmental milestones
  • Body weight, pinnae detachment, eye opening, incisor eruption

  • Righting reflex, visual placing 

  • Negative geotaxis, tactile startle

  • Nest seeking response

  • Auditory startle

  • Bar holding and vertical screen.

  • Clasping behavior

 

Daily activities
  • Barrowing 

  • Home cage activity

  • Nesting

Addiction
  • Alcohol addiction

  • Chocolate or palatable food addiction

  • Compulsive eating

  • Gambling like behavior (Iowa gambling test)

 

Functional tests
  • Locomotor activity

  • Spontaneous locomotor activity

  • Feeding behavior

  • Sexual behavior

  • Heart rate and blood pressure

  • Oxygen saturation, breath rate, pulse and breath distention

IN VIVO  STUDIES

​​Neurological functions
  • Reflexes

  • Motor coordination

  • Sedation

  • Ischemia

  • Epilepsy 

  • Huntington disease 

  • EEG

  • In vivo brain transplants

Surgical techniques
  • Traumatic brain injury (tbi)

  • Glaucoma acute and chronic

  • Neuropathic pain (sciatic nerve injury)

  • Spinal cord lesions

  • Central nervous system and in uterus grafting

  • Microsurgery

  • In utero electroporation

  • Demyelination focal injury (lysolecithin)

  • Toxic transient demyelination (cuprizone)

Brain tumor models
  • In vivo models of glioblastoma (grafts of mouse or human glioblastoma cell lines)

  • In vivo pharmacological treatments

  • MRI-based longitudinal analyses

  • Histological investigations

  • End-point analyses

Administration routes
  • Enteral routes: oral (gavage, capsule, diet), rectal 

  • Parenteral routes: intracerebral, intravenous, intramuscular, subcutaneous, intraperitoneal

  • Local routes: skin, ocular, intranasal, intravaginal, buccal

  • Adeno and retroviral injections

Animal species
  • Mouse (Mus musculus)

  • Rat (Rattus Norvegicus)

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